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[18] The GPX4's appear to play a greater role in the fish GPX system than in mammals

Pol J Microbiol 72(4):443460 Wang Z et al (2019) Protective effects of Pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway

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Biol Psychiatr 2017;81:40210

Studies have shown reductions in C-reactive protein (CRP) and oxidative stress, suggesting protective effects in diabetic nephropathy and cardiovascular disease (135, 157)